from tkinter import *
from tkinter import ttk

root = Tk()
root.title("thing")

mainframe = ttk.Frame(root, padding=(3, 3, 3, 3))
mainframe.grid(column=0, row=0, sticky=(N, W, E, S))

click_hold = StringVar()
click = ttk.Radiobutton(mainframe, text='Click', variable=click_hold, value='click')
hold = ttk.Radiobutton(mainframe, text='Hold', variable=click_hold, value='hold')
click.grid(column=1, row=2, sticky=(W, E))
hold.grid(column=2, row=2, sticky=(W, E))
click_hold.set('click')

left_right = StringVar()
left = ttk.Radiobutton(mainframe, text='Left', variable=left_right, value='left')
right = ttk.Radiobutton(mainframe, text='Right', variable=left_right, value='right')
left.grid(column=1, row=4, sticky=(W, E))
right.grid(column=2, row=4, sticky=(W, E))
left_right.set('left')

click_delay_s = IntVar()
delay_s = ttk.Entry(mainframe, textvariable=click_delay_s, width=3)
click_delay_ms = IntVar()
delay_ms = ttk.Entry(mainframe, textvariable=click_delay_ms, width=3)
delay_s.grid(column=2, row=6, sticky=(W, E))
delay_ms.grid(column=2, row=7, sticky=(W, E))

start_button = ttk.Button(mainframe, text='Start (F6)')

root.columnconfigure(0, weight=1)
root.rowconfigure(0, weight=1)
mainframe.columnconfigure(2, weight=1)
for child in mainframe.winfo_children(): 
    child.grid_configure(padx=5, pady=5)

root.mainloop()